Preclinical Phase

Immunome Inc (NASDAQ: IMNM) shares are trading higher after it published data demonstrating that its COVID-19 antibody cocktail, IMM-BCP-01, potently cleared the omicron variant (BA.1) when tested in vivo in hamsters.  Additional in vitro testing of a SARS-CoV-2 pseudovirus...

Voyager Therapeutics Inc (NASDAQ: VYGR) will present new preclinical data on a family of AAV9-derived TRACER capsids demonstrating cross-species central nervous system transduction at the American Society of Gene and Cell Therapy Annual Meeting. Voyager's TRACER capsid discovery...

Avrobio Inc (NASDAQ: AVRO) announced preclinical data demonstrating the efficacy and safety of AVR-RD-03 gene therapy in infantile-onset Pompe disease.  Pompe disease is a lysosomal disorder caused by a mutation in the GAA gene. The lack of the enzyme encoded by GAA...

Keros Therapeutics Inc (NASDAQ: KROS) announced results from a preclinical study of RKER-012 in a mouse model of pulmonary arterial hypertension (PAH), a type of high blood pressure that affects the arteries in the lungs and the right side of the heart.  The data were shared at...

Phio Pharmaceuticals Corp (NASDAQ: PHIO) presented new preclinical data showing that silencing BRD4 with PH-894 can improve the quality and potency of HER2-targeted CAR-T cells in a CAR-T expansion model.  These new data will be presented at the American Society of Gene &...

Clover Biopharmaceuticals Ltd announced new promising data from a preclinical study on its bivalent vaccine candidate, which combines the trimeric spike antigens from the original SARS-CoV-2 strain and the omicron variant.  Clover developed the SCB-2019 antigen, a stabilized...

Celsion Corporation (NASDAQ: CLSN) has presented its PLACCINE platform technology at the World Vaccine Congress. "PLACCINE is demonstrating the potential to be a powerful platform that provides for rapid design capability for targeting two or more different variants of a single...

Codiak BioSciences Inc (NASDAQ: CDAK) announced new preclinical data from its pan beta-coronavirus vaccine program.  The data demonstrate the potential for the vaccine candidate to induce cross-neutralizing antibody protection against multiple strains and an antigen-specific...

Artelo Biosciences Inc (NASDAQ: ARTL) says its ART27.13 shows promising preclinical results in protecting human muscle cells from cancer-induced muscle degeneration (cachexia) via a CB2 mediated mechanism of action. ART27.13 is a peripherally selective G-Protein Coupled...

Deciphera Pharmaceuticals Inc (NASDAQ: DCPH) announced the presentation of preclinical data for DCC-3116, a ULK kinase inhibitor, combined with KRASG12C inhibitors in non-small cell lung cancer (NSCLC) models. The company shared the data at the American Association for Cancer...

Gain Therapeutics Inc (NASDAQ: GANX) has presented new preclinical data from its Parkinson's Disease (PD) program at the 2022 Synuclein Meeting.  The data show that the lead compound GT-02287 increases the levels and activity of the beta-glucocerebrosidase (GCase) protein,...

Qualigen Therapeutics Inc (NASDAQ: QLGN) shares are surging after highlighting posters at the American Association of Cancer Research (AACR). QN-302 showed potent anti-proliferative activity in a prostate cancer cell panel and anti-tumor activity in an in vivo metastatic...

Schrödinger Inc (NASDAQ: SDGR) presented new preclinical data from its Wee1 inhibitor program at the American Association of Cancer Research (AACR) Annual Meeting. The data show that Schrödinger's Wee1 inhibitors have therapeutic potential for use as monotherapy and as...

LIXTE Biotechnology Holdings Inc (NASDAQ: LIXT) shares are trading higher after the presentation of new data from drug combinations of LIXTE's lead clinical cancer compound, LB-100. Data were shared at the Annual Meeting of the American Association for Cancer Research (AACR)....

Nanobiotix SA (NASDAQ: NBTX) announced new data from a preclinical study evaluating the combination radioenhancer, NBTXR3, with the triple blockade of PD-1, LAG-3, and TIGIT (combination therapy).  The data were published at the 2022 Annual Meeting of the American Association...